Peristeen Irrigation System: A Revolutionary Solution for Bowel Dysfunction

Introduction

Bowel dysfunction can significantly impact a person's quality of life, causing symptoms such as chronic constipation and fecal incontinence. For individuals with neurogenic bowel dysfunction, this condition can be particularly challenging to manage. However, there is a revolutionary solution that has been proven to improve the lives of both adults and children with bowel dysfunction - the Peristeen Irrigation System.

In this comprehensive guide, we will explore the benefits and effectiveness of the Peristeen Irrigation System based on documented studies and clinical trials. We will also delve into the long-term success that can be achieved with Peristeen Plus, the support program offered by Coloplast. Let's discover how Peristeen can provide independence, security, and a better quality of life for individuals with bowel dysfunction.

Documented Studies and Clinical Trials

Numerous studies and clinical trials have been conducted to evaluate the benefits and effectiveness of the Peristeen Irrigation System in both adults and children with neurogenic bowel dysfunction. These studies have consistently shown remarkable results, highlighting the following benefits of Peristeen:

1. Minimizes the likelihood of involuntary bowel leakage
2. Reduces fecal incontinence and constipation
3. Improves symptom-related quality of life
4. Offers independence and a sense of security through better bowel control
5. Helps reduce the frequency of urinary tract infections
6. Can be easily transported when traveling
7. Provides a safe and effective alternative to invasive surgical procedures

These findings are significant as they demonstrate the positive impact that Peristeen can have on the lives of individuals with bowel dysfunction. By effectively addressing the symptoms and challenges associated with this condition, Peristeen offers a viable solution for those seeking to regain control over their bowel function.

Peristeen Plus: Long-Term Success and Support

While the benefits of Peristeen are undeniable, it is important to acknowledge that each individual's experience may vary. Some individuals may find it more challenging to adjust to the Peristeen Irrigation System compared to others. To address this, Coloplast offers the Peristeen Plus program, which provides product and lifestyle support to users.

Enrolling in the Coloplast Care program allows individuals to access dedicated Advisors who are experts in helping people integrate Peristeen Plus into their daily lives. These Advisors provide valuable phone support, offering guidance and assistance tailored to each individual's specific needs. The goal is to ensure long-term success with Peristeen by providing the necessary resources and support throughout the journey.

Regaining control of bowel function is not a quick fix, and it requires time, patience, and support. With the Coloplast Care program, individuals have access to a support system that can help them overcome any challenges they may encounter while using Peristeen. Whether it's troubleshooting technical issues or providing guidance on lifestyle adjustments, the Advisors are there to offer assistance and ensure a successful integration of Peristeen into daily life.

To learn more about the Peristeen Plus program and how it can support your journey towards better bowel control, contact Coloplast Care at 1-855-605-7594 or peristeen@coloplast.com. Alternatively, consult your healthcare professional for more information on how to access this invaluable support system.

Indications and Contraindications

The Peristeen Plus Transanal Irrigation System is specifically designed to instill water into the colon through a rectal catheter, facilitating the evacuation of the lower colon's contents. This system is indicated for use by children, adolescents, transitional adolescents, and adult patients with neurogenic bowel dysfunction who suffer from fecal incontinence, chronic constipation, and time-consuming bowel management procedures.

However, it is important to note that there are certain situations where the use of Peristeen is contraindicated. These include:

• Known anal or colorectal stenosis
• Colorectal cancer (active/recurrent)
• Radiotherapy to the pelvis
• Recent abdomino-perineal surgery
• Active inflammatory bowel disease
• Acute diverticulitis, severe diverticulitis, previous diverticulitis, and diverticular abscess
• Chronic symptomatic diverticular disease
• Recent abdominal, anal, or colorectal surgery
• Recent endoscopic procedures such as polypectomy, biopsy, mucosal resection, or sub-mucosal dissection
• Severe autonomic dysreflexia
• Ischemic colitis
• During the Spinal Cord Shock Phase
• Complex diverticular disease
• Patients who are pregnant and have not used the system before

It is crucial to consult with a healthcare professional to determine if Peristeen is suitable for your specific condition and circumstances. Your healthcare professional will consider individual patient factors and medical history to provide personalized advice and guidance.

The Clinical Evidence: An In-depth Look

To fully understand the benefits and effectiveness of the Peristeen Irrigation System, let's delve into the clinical evidence from various studies conducted on both adults and children with neurogenic bowel dysfunction. These studies provide valuable insights into the positive impact that Peristeen can have on bowel management and overall quality of life.

Clinical Evidence in Adults

In a randomized controlled trial conducted by Christensen et al., 87 adults with spinal cord injuries and neurogenic bowel dysfunction were assigned to either the Peristeen group or the standard bowel care group [3]. The study revealed significant improvements in patient-reported outcomes for bowel function in the Peristeen group compared to the standard care group. The outcomes were measured using validated scoring systems, including the Cleveland Clinic Constipation Scoring System (CCCS), St Mark's Fecal Incontinence Grading System (FIGS), and Neurogenic Bowel Dysfunction Score (NBDS).

Furthermore, several observational studies involving adults have reported positive outcomes when using Peristeen for bowel management. These studies examined patient-reported outcomes, including the severity and frequency of incontinence, severity of constipation, and quality of life measures. The majority of these studies utilized appropriate standardized patient-reported outcome measures, demonstrating the effectiveness of Peristeen in improving bowel function and overall well-being.

It is important to note that some individuals may discontinue using Peristeen due to personal preferences or challenges encountered during the initial adjustment period. However, for those who continue using Peristeen, the studies consistently indicate significant improvements in bowel management and symptom-related quality of life.

Clinical Evidence in Children

Studies focusing on the use of Peristeen in children with neurogenic bowel dysfunction have also yielded positive results. Alenezi et al. conducted an observational study involving 18 children and found that Peristeen improved bowel management in this population [16]. Similarly, Ausili et al. reported positive outcomes in an observational study of 60 children with spina bifida who used Peristeen for bowel management [17]. These studies highlight the benefits of Peristeen in improving bowel control and quality of life in children with neurogenic bowel dysfunction.

While the evidence for children is somewhat limited compared to studies involving adults, the results demonstrate the potential of Peristeen as a safe and effective option for managing bowel dysfunction in pediatric patients. Further research and studies in this area are warranted to provide a more comprehensive understanding of Peristeen's effectiveness in children.

Economic Evaluation: Cost-Effectiveness of Peristeen

In addition to the clinical evidence, an economic evaluation was conducted to assess the cost-effectiveness of the Peristeen Irrigation System. The evaluation compared the use of Peristeen with standard bowel care and analyzed the potential impact on healthcare costs.

The economic evaluation included a de novo cost model developed by Emmanuel et al. [28]. This model considered various factors, such as treatment costs, adverse events, hospitalizations, and the use of resources associated with standard bowel care and Peristeen. The model had a 37-year time horizon, with a discount rate of 3.5% and an NHS and social services perspective.

The findings of the economic evaluation indicated that, on average, Peristeen is unlikely to cost more than standard bowel care over a relevant time horizon. The model demonstrated cost savings associated with the use of Peristeen, considering factors such as reduced rates of stoma surgery, urinary tract infections, and hospitalizations. However, it is important to note that the economic evaluation had some limitations, particularly in terms of the available data and assumptions made in the model.

Cedar, the NHS-academic health care technology research collaboration, conducted a review of the economic evidence and identified several errors in the submitted model [2]. These errors were corrected by Cedar, resulting in a revised cost saving estimate. The corrected model showed that the cost savings due to the use of Peristeen were further reduced. It is crucial to consider the specific context and individual circumstances when evaluating the cost-effectiveness of Peristeen for each patient.

Peristeen: A Revolutionary Solution for Bowel Dysfunction

The Peristeen Irrigation System has emerged as a revolutionary solution for individuals with bowel dysfunction, offering a range of benefits and improvements in quality of life. Through documented studies and clinical trials, Peristeen has consistently demonstrated its effectiveness in minimizing bowel leakage, reducing fecal incontinence and constipation, and improving symptom-related quality of life.

The Peristeen Plus program offered by Coloplast provides essential support and resources to users, ensuring long-term success and a smooth integration of Peristeen into daily life. Enrolling in the Coloplast Care program grants access to dedicated Advisors who can provide personalized guidance and assistance.

While Peristeen is a safe and effective option for many individuals with bowel dysfunction, it is important to consult with a healthcare professional to determine its suitability for your specific circumstances. Your healthcare professional will consider individual patient factors and medical history to provide personalized advice and guidance.

Looking beyond the clinical benefits, economic evaluations have shown that Peristeen is cost-effective compared to standard bowel care. While there may be some limitations in the economic evidence, the overall findings suggest that Peristeen can potentially lead to cost savings in healthcare settings.

In conclusion, the Peristeen Irrigation System has emerged as a game-changer in the management of bowel dysfunction. With its proven benefits, support program, and cost-effectiveness, Peristeen offers individuals with bowel dysfunction a renewed sense of independence, security, and a better quality of life. Embrace the revolutionary solution and take back control of your bowel function with Peristeen.

Information from Coloplast® Care is for educational purposes only. It is not intended to substitute for professional medical advice and should not be interpreted to contain treatment recommendations. You should rely on the healthcare professional who knows your individual history for personal medical advice and diagnosis. Prior to use, refer to product labeling for complete product instructions for use, contraindications, warnings, and precautions.